Product Review: Jane Seymour Natural Advantage All Day Moisture and Nighttime Renewal Complex
Jane Seymour’s Natural Advantage® Nighttime Renewal Complex claims to deliver retinol to the skin using our patented MicroSpongeâ„¢ technology in order to reduce the appearance of fine lines and wrinkles for smoother, younger-looking skin. For $29.95 in a set with a cleanser and a daytime cream, is this product worth the money?
All Day Moisture – Glycolic Acid
Natural Advantage All Day Moisture contains glycolic acid in fairly high concentration. The epidermis is thinned after use of glycolic acid, although the overall thickness of the skin is increased, as treatment has been shown to increase expression of Type 1 Collagen mRNA and hyaluronic acid content in the dermis of the skin.
While glycolic acid is beneficial for the skin, it also makes the skin more photosensitive and thereby susceptible to sun damage. For this reason, many dermatologists recommend using glycolic acid at night rather than during the day, even though glycolic acid is in a day cream here. In addition, many dermatologists also recommend alternating retinol with glycolic acid at night, rather than using both at once (as in the Natural Advantage Line), as both tend to make the skin more photosensitive. Ask your dermatologist if you are unsure if your skin can tolerate it.
All Day Moisture – Sunscreen
According to Dr. Leslie Baumann’s Cosmetic Dermatology, octyl methoxcinnamate and salicylates have a maximum UV absorption at 310 nm to supplement the UVB protection. Oxybenzone and titanium dioxide, found in lower concentrations, are excellent sunblocks for UVA wavelengths. Unfortunately, Baumann cites this Rietschel et. al. study in which oxybenzone is found to be the most common sunscreen agent to cause photoallergic contact dermatitis, so the product may not be particularly good for those with sensitive skin.
In addition, a Baumann-cited study conducted by Tsai et. al found that pre-treatment with 10% glycolic acid caused an increase in UVB sensitivity in white and Asian subjects, and an increase in UVA sensitivity in Asian subjects. Because Natural Advantage All Day Moisture contains a high concentration of glycolic acid, and the Nighttime Renewal Complex contains retinol (another photosensitizing agent), I am surprised that the SPF of this product is not higher.
Night Complex – Patented MicroSpongeâ„¢ technology
Natural Advantage Nighttime Renewal features a patented form of retinol, in which porous softgel microspheres (size range in between 5 to 300 μm) contain retinol around a soft gelatin shell filled with retinol-impregnated microparticles. It has been proposed in the Journal of Current Drug Delivery that microsponge delivery methods can “provide increased efficacy for topically active agents with enhanced safety, extended product stability.” That’s the good, promising part.
The unfortunate part of the product is that it does not make its concentration of retinol known. According to Dr. Zoe Diana Draelos, M.D., in the January 2005 supplement to Cosmetic Dermatology, formulation of an ingredient (including its concentration) plays a strong role in a product’s performance. Similarly priced products like Neutrogena Healthy Skin Anti-Wrinkle Cream contain less than 0.2% retinol. Slightly more expensive Skinceuticals Retinol 0.5 and Skinceuticals Retinol 1.0 contain 0.5% retinol and 1.0% retinol, respectively, while Advanced Skin Therapeutics’ Green Cream 6 and Green Cream 9 contain 0.6% retinol and 0.9% retinol, respectively.
Without knowing the concentration of retinol, and without independent studies demonstrating to what extent microspheres increase product efficacy (is 0.2% with encapsulation similar to 0.5% without?), it is impossible to know if this is a superior retinol product. At this time, it would seem safe to compare it to Neutrogena Healthy Skin Anti-Wrinkle Cream, with a novel delivery system.
Night Complex – Vitamin C and Vitamin E…but with Vitamin A?
Again, good (even great) news and bad news. First, the good. Vitamin C and vitamin E are network antioxidants that synergistically enhance the power of one another, increasing sun protection and reducing free radical damage by impede or slowing the free radical chain reaction. Two favorites for sure!
Now, the bad. Two concerns about this formulation: One, it has been proposed in this study in the International Journal of Pharmaceutics that vitamin C encapsulated as ascorbyl palmitate is “not adequate” in selected long-term microemulsions. The study proposes that sodium ascorbyl palmitate is used instead. Of course, this concern may be disregarded if the patented microsponge delivery system is improved over the system used in the microemulsions study.
Which brings concern number two: It has been reported here in the Journal of Dermatological Surgery that vitamin C and its derivatives should be formulated at a pH under 3.5. Unfortunately, the pH optimal for retinol esterification (which may be thought of simply as activation) has been reported in the Journal of Investigative Dermatology to be between 5.5-6.0. With that said, the pH for each ingredient in the formulation is most likely suboptimal. It would most likely be better to use a vitamin C and E product in the morning under sunscreen (to get the sunblock-boosting effects) and use a night retinol cream without acidic vitamin C.
Overall: decent, but not great
Overall, the product line contains some excellent ingredients that have been proven to work in several scientific studies. Microencapsulated retinol and vitamin C are revolutionary, although one cannot know their efficacy compared to non-microencapsulated creams with those ingredients in higher concentrations and/or at more stable pH levels. [For now, until more research is done, I personally am staying with higher concentrations and more stable pH levels (i.e., retinol and vitamin C at 1.0% and 15.0%, respectively, and in separate formulations).]
Furthermore, while glycolic acid and retinol both make substantiated differences in the skin, using both in conjunction may prove too irritating for those with more sensitive skin. Add in the fact that glycolic acid and retinol make skin photosensitive with the fact that the day cream only provides SPF 15, and this line gets a 6.5/10.
Natural Advantage All Day Moisture Ingredients
Active Ingredients: Octyl Methoxycinnamate, Oxybenzone, Octyl Salicylate, Titanium Dioxide.
Other Ingredients: Water, Glycolic Acid, Glycerin Steareth-20, Cetyl Alcohol, DEA-Cetyl Phosphate, Dimethicone, Hexyl Laurate, Steareth-2, Thea Sinensis Extract, PEG-100 Stearate, Ammonium Hydroxide, Glyceryl Stearate (and) PEG-100 Sterate, Acrylates Copolymer, Propylene Glycol (and) Diazolidinyl Urea (and) Methylparaben (and) Propylparaben, Octyldodecyl Neopentanoate, Panthenol, Tocopheryl Acetate, Magnesium Aluminium Silicate, Xanthan Gum, Allantoin, Disodium, EDTA, Methylparaben, Propylparaben, Matricaria Oil.
Use of this product is covered by one or more of the following U.S. Patent Nos.: 4,690,825 and 5,145,675 under license from Cardinal Health PTS, LLC; 5,091,171; B1 5,091,171; 5,547,988; 5,385,938; 5,389,677; and Appl. No. 06/945,680 under license by Tristrata Technology, Inc.
Natural Advantage Nighttime Renewal Complex Ingredients
Water, Capryic/Capric Triglyceride, Emulsifying Wax, Glycerin, C 10-30 Cholesterol/Lanosterol Esters, Cetyl Ricinoleate, Cetyl Alochol, Dimethicone, Benzyl Alcohol, Cyclomethicone, Retinol, Tocopheryl Acetate, Ascorbyl Palmitate, Methyl Metacrylate/Glycol, Dimethacrylate, Crosspolymer, Bisabolol, PEG-10 Soya Sterol, Magnesium Aluminium Silicate, Stearic Acid, Methylparaben, Phenoxyethaol, BHT, Disodium, EDTA, Proply Gallate, Polysorbate 20, Triethanolamine.
Use of this product is covered by one or more of the following U.S. Patent Nos.: 5,851,538; 4,690,825; and 5,145,675 under license from Cardinal Health PTS, LLC; 5,091,171; B1 5,091,171; 5,547,988; 5,385,938; 5,389,677; and Appl. No. 06/945,680 under license by Tristrata Technology, Inc.



How do I ordor this product without a credit card
THIS CREAM IS THE GREATEST I HAVE BEEN USING IT FOR 1 MONTH AND I SEE A DRAMATIC DIFFERENCE IN MY SKIN, AND SO DOES EVERONE ELSE. ALL MY FRIENDS THINK I HAD BOTOX DONE. I NOTICED THE DIFFERENCE AFTER JUST 1 WEEK. ALL I KNOW IS I HAVE SPENT THOUSANDS OF DOLLARS ON CREAMS AND DID NOT GET THE EFFECT LIKE JANE SEYMOURS CREAM.
I would like for you to know that I seen your commercial on TV and I was very interested in your product. I called on Sunday, January 27th around 11am. and I was totally discouraged when the representative answered the phone she was abrupt, was very inpatient and very rude to say the least and kept repeating her answer when I was asking specific questions to her. She was patient enough to even want to answer a few questions that I had on buying the product. I hung up on her and called shortly thereafter, hoping I would get another representative, when the phone was picked up, no one answered but I heard other representative talking from the background. I called a couple more times and got the same thing. At this point, I gave up but wanted you to know that your product is not setting a good example nor good service for interested customers!!!
I actually had the opposite experience with customer service. Every time I’ve called they have been friendly and accommodating. There was a billing error I called about recently and I asked if I could quit the automatic shipments and just order when I needed it and noone tried to pressure me to stay with the program but instead I was told it was not a problem and they apologized for the billing mistake and explained how it happened. I like the consistency and scent of the product and have seen some slight improvement though I might see more if I used it more regularly. So far I’ve been satisfied with the product and the service.
Interested in ordering this product…would like to call in ..but I do not see or maybe I missed the toll free number given on the infomercial or on the website….can you send it to me?
Thank you
CALLED TO ORDER THE PRODUCT ON 2/10. THEY SAID IT WOULD BE SENT OUT PRIORITY MAIL AND I STILL HAVEN’T RECEIVED IT. NEED YOUR 800 NUMBER TO CALL AND CHECK ON MY ORDER. PLEASE ADVISE.
I would like to try this for one month. When I try and order it won’t let me because I live in Canada. It says I don not have a state. Am I allowed to buy it from Canada? Am I allowed to try it for a month and not sign up for every month yet? Coleen Anderson
Edmonton AB. Canada
coljima@shaw.ca
I like the product, but the frustration involved in actually GETTING the product is awful!!! I got all of my kit except the eye cream shipped 1/16. (It took 2-3 calls to get the partial shipped.) I have called every 2 weeks to check status – each phone call is a different story. I have twice been assured that the product will ship “by the middle of the month” but it does not. (My new projected ship date is mid-March). Jane is on at least 2 channels selling more product every time I turn the TV on, and I still can’t get my order. I am going back to Selleca Solution. It is a good product that actually ARRIVES as promised. I have never been so frustrated with a product. (By the way, if you go to the Natural Advantage site and try to submit a comment, it will not go through – it will tell you over and over again that the security code does not match and not let you submit. Guess that’s one way to cut down on complaints.)
[...] part of the product Jane sells is that it does not make its concentration of retinol known. Product Review: Jane Seymour Natural Advantage All Day Moisture and Nighttime Renewal Complex « Futu… If you’re looking for a face-lift in a bottle, you won’t find it in over-the-counter [...]
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I ordered this product over 7 Days ago by e-mail I would like to know when I will recieve this.
Thank you
Elke Menard
I have no idea, as I am not affiliated with the company. My apologies!
re:#10 It says on the confirmation e-mail that it will take 2-3 weeks for shipping.
I ordered mine on march 6th and it shipped yesterday. They said it should now take 5-7 days for delivery.
To Janice Greene:
Umm . . . Not to be impolite, but you’re venting in the wrong place! This site is not affiliated with the products. Rather, from what I interpret, it is a gold mine of invaluable information – which includes reviews of such products (i.e., ingredients, effectiveness, etc.)
Diane Wedler
My mother sent for Natural Advantage which has been sent but not recieved as yet.
She is ill in the hospital and I want to cancel any more that may be sent after this order till we find out how she will be.
If things go well I will re-order later.
Thank you
Her Daughter.
Marg.
The order is under M.B.Anderson
6–200 North Corfield Street
Parksville B.C.V9P2S5
Canada
Hi,
I apologize, but I do not have anything to do with the ordering or shipment of Jane Seymour products. Please do not send me your comments on ordering or shipment, because I am not able to help you. Thank you!
I am still waiting for them to stop billing my credit card. I have enough to last me for months and they still use my card and I have to call my company and stop them and yes, they still owe me money. The product is good but, the billing dept is terrible. Of course they send it from ON Canada what is going on with this company.
I am So VERY disappointed in this product. At first, I thought it was OK, but with no real results (the first 2-3 weeks) NOW I have White Blotches so severe and Large that others are Noting It- they are like a Line going across on top of each cheek bone. It is so bad; I do not know what to do. I am 42yrs old and do not go out in the sun w/out protection, nor do I tan at a salon. I Look Awful. I contacted them to cancel any shipments and to ask what to do. I Still got a Charge and Shipment and I still do not get a direct response to my issue. I have tried to get my money back for the shipment to no avail and now i am left with serious Damage. The only positive thing is that This product actually HELPED my hormonal Acne and I had No reaction to it, like all other products.
Can anyone give me the toll free number for Natural Advantage. I have already been billed twice and have not received any products. Thanks.
I too experienced horrible customer service when dealing with this company. They refused to sell it to me when I needed it – I could only have the auto shipping done every 30 days. Also, their priority mail – which should have been 2-4 days turned into 3 weeks! Again, just poor customer service. I’ll be looking for an alternative product.
The number for customer service for Natural Advantage is 800-435-7383 if you need to reach the company by phone.
This number is 877-435-7383 not 800. sorry for the mistake
Please email me back, I don’t have phone number to change my upcoming order. I have closed the acct. you were charging products too. I need you to email me so I can call you and give you new acct. and change in product before next one is sent. i hope you get this soon enough. Thank you
barbara chapmond
2102895886
I am NOT the person to contact about ordering information of Jane Seymour products! I only reviewed the product, and I do not sell them. Please do not send me your complaints about orders, as I can do nothing. Thank you!
I have used the night cream for the last 3 years and have been satisfied. The order I received this month was a disappointment. The night cream is so thin that I should call it a lotion and not a cream. It just runs out of the tube freely. I feel something is wrong and would like a replacement.
I absolutely love this product, however I don’t want to
pay for it every single month, as I found it lasts longer.
So I tried to order it just for one month, and finding out
I had to pay an additional $10—-that just doesn’t seem fair.
Please re-consider this: For those of us who only want to order it by the month, as is needed, why should we be penalized?
I hope you think about this, and IF you change, please e-mail me as I’d love to order more, but am unwilling to be charged extra just for something I don’t need monthly.
Thanks,
Tory Christman
Thank you for your honest assessment of this product. I’m considering ordering, I think it would help with my breakouts as well as fine lines. I appreciate that you say what is good and what you think could be better.
I think it is strange that so many who read your review think you are the company! Good luck with that…
Jane Seymour should be ASHAMED of herself!!! I got this product and, a few weeks later, another box, and more charges to my credit card!!! At triple the rate of the first box!!! And I specifically asked to NOT receive multiple boxes, just the trial box. I called and they WON’T take the NEW charges off my credit card until I PAY for mailing back the new box and I WASTE MY TIME going to the post office. THEN they STILL will charge me for their postage and handling! SCAM ALERT! This is a scam. I HATE Jane Seymour (her voice answers the 1-800 #). She is Wh@r$ing herself all the way to the bank! Shame on you Jane Seymour!
Is your product curelty free (not tested on animals?)